mTOR Signaling Pathway | Nutrient and Cell Stress Regulation

The video tutorial provides an in-depth analysis of the mTOR signaling pathway, highlighting its role in regulating growth, proliferation, and survival. It explains the two complexes of mTOR, the influence of growth factors and insulin on mTOR activation, and the mechanisms leading to its inhibition. The tutorial also covers the internal and external regulation of mTOR complexes, including feedback loops and the role of various proteins and amino acids in modulating mTOR activity.

Identify the major cellular stressors that inhibit mTOR signaling.

Discuss the role of amino acids like arginine and leucine in mTOR signaling.

What is the significance of negative feedback inhibition in mTOR signaling?

How do the proteins MLST 8, Raptor, and Deptor regulate mTOR complex 1?