Complement Anaphylatoxins (C5a, C3a, C4a)

The video tutorial explains the three pathways of complement activation, focusing on the role of C3 convertase in the lectin and classical pathways. It highlights the importance of anaphylatoxins, particularly C3A and C5A, in promoting inflammation, chemotaxis, and phagocytosis. The tutorial also covers how these components enhance the immune response by guiding white blood cells to infection sites and facilitating mast cell degranulation, which releases histamine to increase blood flow and vascular permeability.

What are the two components that C3 convertase splits the protein C3 into?

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Explain the role of C3A and C5A in promoting inflammation.

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Describe the process of chemotaxis and how anaphylatoxins influence it.

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How do C3A and C5A enhance the process of phagocytosis?

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What is the significance of integrin upregulation in phagocytosis?

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What are the effects of histamine release from mast cells during an immune response?

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Discuss the importance of increased vascular permeability in the context of an immune response.

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