Hydroboration/Oxidation: Theory and Examples

This video tutorial covers hydroboration oxidation, a chemical reaction that adds hydroxyl groups to the least substituted side of an alkene, known as anti-Markovnikov addition. The video explains the reagents used, such as borane and tetrahydrofuran, and highlights the reaction's stereochemistry, including the formation of enantiomers. Practice problems are provided to illustrate the concepts, and the limitations of the reaction, particularly with aromatic compounds, are discussed.

How can one predict the products of hydroboration oxidation reactions?

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What happens when hydroboration oxidation is attempted on an aromatic compound?

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What is the outcome when both sides of a double bond are equally substituted during hydroboration oxidation?

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In what scenarios is hydroboration oxidation considered useful?

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