Human Sulfur Assimilation: ATP Sulfurylase and ASP Kinase

The video tutorial explains the process of sulfate metabolism in humans, focusing on the transformation of sulfur into its most usable form, sulfate. It details the formation of PAPS (phospho adenosine phosphate sulfate) through a two-step enzymatic process involving ATP Sulfurylase and APS kinase. The tutorial highlights the role of the liver in transferring sulfates to various molecules, which aids in excretion and storage. The energetically expensive nature of this process, requiring two ATP molecules for each sulfate transfer, is emphasized, underscoring its importance in human metabolism.

Explain the two-step process involved in the formation of PAPS.

What are some examples of molecules that undergo sulfation, and why is this process important?