Rare Genetic Mutation May Help Drugmakers Battle Obesity

The video discusses a new drug initially targeting people with a liver condition called Nash, with hopes to expand its use for weight loss and preventing diseases like diabetes. The drug is modeled on a genetic mutation that allows some people to eat without gaining weight. Research is ongoing, with comparisons to past drugs like Topamax, which had appetite suppression as a side effect. Commercial viability remains a concern.

What was the reason Johnson and Johnson decided not to pursue a similar drug?

What side effect of Topamax is mentioned in the text?