US Peace Corps evacuates volunteers amidst ebola threat

What do you think the phrase 'Open up' signifies in a broader context?

In what situations might someone say 'Open up' to another person?

How can the phrase 'Open up' be interpreted in terms of emotional expression?

What are some possible responses to the command 'Open up'?

Can you think of any literary works or songs that use the phrase 'Open up'? What do they convey?