Cytokines and Immune Responses

The video tutorial explores the roles of cytokines and chemokines in immune cell communication. It covers the naming conventions and functions of various cytokine families, including Th1, Th2, Th17, and regulatory T cells. The tutorial also delves into chemokines, explaining their role in cell movement and organization within lymphoid tissues.

What is the primary function of cytokines in the immune system?

• To destroy pathogens directly

• To transport nutrients

• To communicate between immune cells

• To provide energy to immune cells

Which cytokine is crucial for T cell survival and proliferation in a Th1 response?

• IL-4

• IL-2

• IL-10

• IL-17

What is the main characteristic of a Th2 immune response?

• Suppression of B cell activity

• Dominance of antibody action

• Activation of CD8 T cells

• Direct destruction of viruses

Which cytokine is known for driving eosinophil development in the bone marrow?

• IL-10

• IL-22

• IL-12

• IL-5

What is the primary role of Th17 cytokines?

• To control intracellular pathogens

• To promote humoral responses

• To suppress immune responses

• To recruit neutrophils for extracellular bacteria control

Which cytokine helps polarize helper T cells to a Th17 phenotype?

• IL-10

• IL-23

• IL-4

• IL-2

What is the function of regulatory T cells (Tregs) in the immune system?

• To produce antibodies

• To activate B cells

• To dampen immune response and prevent autoimmunity

• To enhance immune response

Which chemokine family is characterized by two adjacent cysteine residues?

• CCR family

• CXC family

• CC family

• CXCL family

What is the role of CXCL8 in the immune response?

• To recruit neutrophils to infected tissues

• To suppress T cell activity

• To activate B cells

• To recruit eosinophils

Which chemokine is secreted by follicular dendritic cells to recruit B cells?

• CXCL8

• CCL18

• CXCL13

• CCL21