Alternative Pathway of Complement Activation

The video tutorial by Kevin Tolkoff explains the complement activation pathways: classical, lectin, and alternative. The classical pathway requires antibodies, while the lectin pathway is antibody-independent, relying on mannose residues. The alternative pathway is unique, with baseline activity due to C3 hydrolysis. The video details the formation of the membrane attack complex, which disrupts pathogen membranes. The tutorial concludes with a preview of the next video, focusing on the functions of A fragments in the complement system.

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