Protoporphyrinogen Oxidase: Physiology, Biochemistry, and Organic Mechanism

The video tutorial explores the penultimate step of heme synthesis, focusing on the enzyme protoporphyrinogen oxidase. It explains the transformation of protoporphyrinogen to protoporphyrin, highlighting the aromaticity and Huckel's rule. The video also discusses variegate porphyria, an enzyme deficiency, and delves into the enzyme's mechanism, including FAD chemistry and detailed mechanistic steps.

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