Effect of Ethidium Bromide on Supercoiling & Electrophoresis

The video tutorial explains DNA topoisomers, focusing on how their shapes affect movement through agarose gel. It discusses the role of ethidium bromide in inducing positive supercoiling and its carcinogenic nature. The tutorial uses graphs to illustrate sedimentation velocity and supercoiling, and describes experiments to determine DNA's original state using ethidium bromide.

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