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The video covers the start of the world's largest coronavirus vaccine study with 30,000 volunteers, including details on trial sites and the use of placebos. It also discusses major retailers like Target and Walmart closing on Thanksgiving to limit Black Friday crowds, with plans to offer discounts starting in October. Additionally, the video reports on violent protests in several US cities, including Portland, Virginia, and Texas. Finally, it provides information on how viewers can stay updated with Newsy through social media and other platforms.

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