Why Shouldn't You Take Medicine with Grapefruit Juice?

The video explains why grapefruit juice is often warned against in drug commercials. Grapefruit contains furanocoumarin, which deactivates the enzyme CYP3A4 in the small intestine. This enzyme normally helps metabolize drugs, so its deactivation leads to higher drug absorption, potentially causing overdose and liver issues. The video advises consulting a doctor if you consume grapefruit juice while on medication and suggests switching to orange juice as a safer alternative.

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