Metronidazole | Bacterial Targets, Mechanism of Action, Adverse Effects

This video lesson covers the antibiotic metronidazole, also known as Flagyl. It discusses its properties, absorption, and distribution, highlighting its effectiveness against obligate anaerobes and some protozoa. The mechanism of action involves DNA damage through reactive oxygen species. The video also outlines infections treated by metronidazole, such as Clostridium difficile and brain abscesses, and details adverse reactions, including gastrointestinal and nervous system effects. A key warning is to avoid alcohol consumption during treatment due to disulfiram-like reactions.

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