Tropical Sprue | Causes, Pathogenesis, Signs & Symptoms, Diagnosis, Treatment

Tropical sprue is a gastrointestinal condition affecting the small intestine, leading to malabsorption. Its exact cause is unknown but is likely infectious, possibly bacterial. It occurs in tropical regions like Cuba, Haiti, and India. The condition causes enterocyte damage, leading to symptoms like diarrhea, weight loss, and nutrient deficiencies, particularly in vitamin B12 and folic acid. Diagnosis involves excluding other causes and identifying villous atrophy and macrocytic anemia. Treatment includes vitamin supplementation, IV fluids, and antibiotics like tetracycline.

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