Nucleotide Metabolism | Purine Biosynthesis 2: IMP to AMP & GMP

The video explains the biosynthesis of adenylate (AMP) and guanylate (GMP) from inosine monophosphate (IMP). It details the enzymatic pathways for converting IMP into AMP and GMP, highlighting the role of enzymes like adenylosuccinate synthetase and IMP dehydrogenase. The video also discusses the regulatory mechanisms that balance AMP and GMP synthesis, emphasizing allosteric regulation and feedback inhibition. The importance of maintaining a balance between purine nucleotides is underscored, with ATP and GTP playing crucial roles in this regulation.

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