Researchers use gene-editing to create mice with same-sex parents

The video tutorial discusses a study on gene editing and stem cells, focusing on techniques to produce healthy mice with two mothers. Researchers used haploid embryonic stem cells, which contain half the usual number of chromosomes, and combined DNA from two different mice. CRISPR technology was employed to delete imprinting from specific DNA regions, making the genetic material appear more male. These modified stem cells were injected into eggs of another female mouse, resulting in the development of embryos and the birth of 29 live mice from 210 embryos.

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