Serine Racemase: Mechanism and Inuition

Serine Racemase: Mechanism and Inuition

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Science, Chemistry

University

Hard

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The video tutorial explains the conversion of L-serine to D-serine through a pyridoxal phosphate-dependent racemization catalyzed by the enzyme serine racemase. It details the mechanism, including the role of pyridoxal phosphate, the beta elimination process, and the importance of stereochemistry and enzyme conformation. The formation of a quinonoid intermediate and the inversion of stereochemistry are also discussed, concluding with the regeneration of the enzyme's resting state.

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OPEN ENDED QUESTION

3 mins • 1 pt

What new insight or understanding did you gain from this video?

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