Gabriel Amine Synthesis

Gabriel Amine Synthesis

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Interactive Video

Chemistry, Science

11th Grade - University

Hard

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The video tutorial covers the significance of name reactions in organic chemistry, focusing on the Gabriel synthesis for primary amine production. It explains the challenges of primary amine synthesis using SN2 reactions and how Gabriel's method overcomes these issues. The mechanism involves using thalamide as a protected ammonia surrogate to prevent multiple alkylations. The tutorial also discusses potential side reactions, such as O alkylation, and modern variations of the synthesis to expand its scope.

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OPEN ENDED QUESTION

3 mins • 1 pt

What new insight or understanding did you gain from this video?

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