The video explains arsenic poisoning mechanisms, focusing on arsenate's disruption of glycolysis and arsenite's impact on the TCA cycle. It details how arsenate mimics phosphate, affecting ATP production, and how arsenite inhibits key enzymes, disrupting metabolism. An antidote, 2-3 dimer capto propanol, is discussed for its ability to restore enzyme function. The video concludes with a historical anecdote about President Harding's alleged arsenic poisoning.

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