What Your Family History Can’t Tell You

The video explores the role of family history and genetic mutations in assessing disease risk, highlighting the limitations of family history alone. It introduces polygenic risk scores, which consider multiple genetic variants to predict disease risk more accurately. Genome-wide association studies (GWAS) are crucial in identifying these variants. The video also discusses the potential of polygenic risk scores in early disease prediction and prevention, while noting the current limitations due to a lack of diversity in genetic studies.

What new insight or understanding did you gain from this video?