Pharmacology of Alzheimer's Disease

The video tutorial explores the pathophysiology of Alzheimer's disease, focusing on neuron degradation in the cerebral cortex and the role of acetylcholine. It explains the biochemical pathway of acetylcholine, its degradation by acetylcholinesterase, and the use of inhibitors like donepezil, rivastigmine, and galantamine to preserve acetylcholine levels. The tutorial also discusses the NMDA receptor's role in memory and learning, and how memantine, an NMDA receptor antagonist, can help prevent neuron loss by reducing excitotoxicity.

What new insight or understanding did you gain from this video?