GABA Biosynthesis and Catabolism

The video explains the synthesis of GABA from glutamate and its role in the central nervous system. It highlights the ineffectiveness of GABA supplements due to their inability to cross the blood-brain barrier and the endogenous production of GABA by neurons. The video also covers the metabolic pathway of GABA degradation, which involves conversion into succinate for entry into the TCA cycle, and discusses the compartmentalization of GABA metabolism within neurons.

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