Citrate Synthase

The video explains the mechanism of citrate synthase, focusing on the conversion of oxaloacetate and acetyl CoA into citrate. It covers the aldol condensation and hydrolysis steps, detailing the role of active site residues like histidine and aspartate. The process involves proton transfer, nucleophilic attack, and the formation of Citroyl-CoA, leading to the final product, citrate.

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