Isocitrate Dehydrogenase

The video explains the mechanism of isocitrate dehydrogenase, focusing on its role in oxidative decarboxylation. It details the conversion of isocitrate to alpha-ketoglutarate, highlighting the involvement of cofactors like manganese and NAD+/NADP+. The process involves oxidation, decarboxylation, and stabilization of intermediates, with a critique of a reaction diagram to clarify the sequence of events.

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