Hormone action-gene activation

Steroid hormones regulate body functions by:

• Binding to receptor on the cell surface

• Activating adenylyl cyclase enzyme

• Crossing the plasma membrane of target cell

• Using second messenger cAMP

What is produced after transcription of activated gene in the nucleus due to steroid hormone action?

• DNA

• Protein kinase

• mRNA

• ATP

What happens after the steroid hormone binds with its receptor in the cytoplasm?

• Formation of cAMP

• Immediate enzyme activation

• Hormone-receptor complex enters nucleus

• Hormone breaks down

Arrange the correct sequence in the mechanism of steroid hormone action.

1.​ ​ (a)  

2.​ ​ (b)  

3.​ (c)  

4.​ (d)  

5. 5.​ (e)  

• Steroid hormone diffuses into target cell
• Bind to receptor forming hormone-receptor complex
• Activates gene
• Transcription of DNA
• Translation occur to produce protein
• Steroid hormone is absorbed by the skin
• Hormone-receptor complex is broken down
• Protein is released into the bloodstream

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