Natural Killer Cells: How Do They Kill Selectively?

The video explains the role of natural killer (NK) cells in the immune system, highlighting their similarities to cytotoxic T cells. Unlike adaptive immune cells, NK cells are part of the innate immune system and can target a variety of abnormal cells through immunological surveillance. They identify abnormal cells by detecting the absence of normal MHC proteins or the presence of abnormal antigens. NK cells induce apoptosis in target cells using perforins and granzymes, ensuring controlled cell death without spreading pathogens.

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