Understanding Macrolides

Which type of bacteria do macrolides primarily target?

• Gram-positive bacteria

• Gram-negative bacteria

• Both gram-positive and gram-negative bacteria equally

• Neither gram-positive nor gram-negative bacteria

Which of the following infections are macrolides NOT effective against?

• Staphylococcal infections

• Streptococcal infections

• Chlamydia infections

• Enterococcal infections

Which of the following is a newly added macrolide used for C. diff infections?

• Azithromycin

• Clarithromycin

• Erythromycin

• Fidaxomicin

How do macrolides generally affect bacteria?

• They alter bacterial DNA

• They kill bacteria directly

• They inhibit bacterial protein synthesis

• They enhance bacterial growth

Which part of the ribosome do macrolides target?

• 30S subunit

• DNA gyrase

• 50S subunit

• RNA polymerase

What should a nurse confirm before administering macrolides?

• Patient's blood type

• Patient's age

• Patient's allergy status

• Patient's dietary preferences

What should be monitored to assess the effectiveness of macrolide treatment?

• Patient's appetite

• Patient's sleep patterns

• Patient's temperature and blood pressure

• Patient's weight

Which adverse effect is associated with a prolonged QT interval?

• Cardiac issues

• GI upset

• Ototoxicity

• Liver problems

What is the mnemonic used to remember the adverse effects of macrolides?

• RISK

• SAFE

• CLOG

• FACE

Which symptom is NOT a sign of liver problems associated with macrolides?

• Increased appetite

• Jaundice

• Dark colored urine

• Abdominal pain