Protein Sorting and Nuclear Transport Quiz

What is the primary function of the nuclear pore complex (NPC)?

• To replicate DNA

• To synthesize proteins

• To produce ribosomes

• To facilitate gated transport between the nucleus and cytosol

Which signal is necessary for a macromolecule to enter the nucleus?

• Endoplasmic reticulum signal

• Nuclear export signal (NES)

• Nuclear localization signal (NLS)

• Signal peptide

What role does Ran GTP play in nuclear import?

• It hydrolyzes ATP for energy

• It facilitates the release of cargo into the nuclear lumen

• It transports cargo back to the cytosol

• It binds to the cargo directly

How does the nuclear export receptor differ from the import receptor?

• It does not interact with Ran GTP

• It is not encoded by the karyopherin gene family

• It binds to different nucleoporins

• It requires a different signal sequence

What is the function of nuclear transport factor 2 (NTF2)?

• To bind cargo for export

• To hydrolyze GTP

• To synthesize nucleoporins

• To transport Ran GDP into the nucleus