IB Biology: C2.1-Receptors with tyrosine kinase activity

What are Receptor Tyrosine Kinases (RTKs)?

• Proteins that only exist in the extracellular space.

• Transmembrane proteins with a cytosolic part that has tyrosine kinase activity.

• Proteins that only catalyze the transfer of phosphate groups.

• Intracellular signaling molecules that bind directly to DNA.

Are you enjoying the video lesson?

• Yes

• No

What is the general function of a kinase?

• To break down proteins into amino acids.

• To synthesize new proteins from amino acids.

• To catalyze the transfer of phosphate groups.

• To transport molecules across the cell membrane.

What is the initial step in the activation of Receptor Tyrosine Kinases (RTKs)?

• Transphosphorylation of tyrosine residues.

• Dimerization of the receptor monomers.

• Ligand binding to the receptor.

• Phosphorylation of downstream proteins.

What process occurs immediately after the dimerization and activation of Receptor Tyrosine Kinases (RTKs)?

• Gene regulation.

• Transphosphorylation.

• Binding of SH2 domain proteins.

• Protein degradation.