TCB - W11

NK cells are activated either by low or absent MHC-I on a target cell or via their FcγRIII receptor recognizing antibodies on the target, leading to target cell killing.

• Correct

• Incorrect

What role do regulatory T cells play in tumor progression: promoting or inhibiting the tumor?

• Promote

• Inhibit

Which of the following best describes the concept of cancer immunoediting?

• Tumor cells always escape immune detection and grow uncontrollably.

• The immune system both suppresses tumor growth (protective) and shapes tumor immunogenicity (pro-tumor) through elimination, equilibrium, and escape phases.

• Cancer progression is independent of the immune system.

• Tumor cells promote immune cell activation to eliminate surrounding healthy tissue.

Match each cancer immunotherapy approach with its correct description:

Therapies:

• 1. Monoclonal Antibody Therapy

• 2. Cancer Vaccine

• 3. Adoptive Cell Therapy

• 4. Immune Checkpoint Inhibition

• Descriptions:

A. Stimulates the patient’s immune system to recognize tumor antigens, often through delivery of tumor-specific peptides or dendritic cells.

B. Uses antibodies to block inhibitory receptors like PD-1 or CTLA-4, unleashing T cell responses against tumors.
C. Uses antibodies designed to specifically target tumor antigens, leading to tumor cell killing or immune activation.
D. Involves transferring ex vivo–expanded tumor-specific T cells back into the patient to attack tumor cells.

(a)  

你對哪一種免疫療法最感興趣呢？

• Monoclonal Antibody Therapy

• Cancer Vaccine

• Adoptive Cell Therapy

• Immune Checkpoint Inhibition