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Blood types - Printable Science Worksheets 7th Grade - Wayground

Blood types

Sherri Kratzer

Created by Sherri Kratzer

18 questions

7th Grade

Science

Updated Oct 2026

This Grade 7 science worksheet helps students connect blood type structure, compatibility, and inheritance. Across 18 questions—17 multiple-choice items and 1 multiple-select item—students identify red blood cell antigens, determine which antibodies accompany type A blood, distinguish ABO and Rh blood types, and apply the concepts of universal donors and universal recipients. The questions also address codominance, multiple alleles, and the genetic basis of blood type. Students then use genotype reasoning to predict offspring blood types and calculate probabilities for crosses such as heterozygous type A parents, AA and AB parents, two AB parents, and type O and AB parents. These examples give learners practice translating parental genotypes into possible child phenotypes rather than memorizing blood-type labels alone. Designed for Grade 7 science instruction, this free printable worksheet includes a complete answer key for checking understanding, reviewing misconceptions, or supporting independent practice.

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Blood types

Total questions: 18

Name
Class
Date
1.

Name the proteins on the surface of red blood cells.

a)

Antibodies

b)

Antigens

c)

Plasma

d)

Collagen

2.

What type of antigens can be found on the surface of RBC's when someone has blood type O?

a)

A

b)

B

c)

AB

d)

none

3.

What antibodies can be found when someone has blood type A?

a)

none

b)

A

c)

B

d)

A and B

4.
What type of blood is the universal donor?
a)
O
b)
AB
5.
which blood type is the universal donor (all people can receive it)?
a)
O
b)
AB
c)
A
d)
B
6.

Which of the following is true about blood type O?

a)

It contains antigen A only.

b)

It contains antigen B only.

c)

It contains both antigen A and antigen B.

d)

It doesn’t contain antigen A or antigen B.

7.
Which blood type is the UNIVERSAL DONOR?
a)
O+
b)
O-
c)
AB+
d)
AB-
8.
Which blood type is the universal recipient?
a)
AB+ 
b)
AB-
c)
O+
d)
O-
9.

What inheritance patterns makes the blood type AB possible?

a)

incomplete dominance

b)

multiple alleles

c)

codominance

d)

total dominance

10.
If two parents are heterozygous for type A blood, what is the probability that their offspring would have type O blood?
a)
100 %
b)
75%
c)
50%
d)
25%
11.
If a father is AA and a mother is AB, what is the probability for a child with AB blood? 
a)
0%
b)
25%
c)
50%
d)
75%
12.
If two parents have type AB blood, what is the probability that their child will have type O blood?
a)
0%
b)
25%
c)
50%
d)
100%
13.
An individual's blood type is determined by
a)
environment
b)
genetics
c)
both environment and genetics
d)
your children's blood type
14.
What are the blood types of the possible children that a woman (type O) and man (type AB) can have?
a)
O and AB
b)
O and A
c)
O and B
d)
A and B
15.

A father has type AB blood and the mother has type O. What percentage of their offspring would you expect to have?

a)

Type A, 25%, Type B 25%, Type AB 25%, Type O 25%

b)

Type A 50%, Type B 25%, Type AB 25%, Type O 50%

c)

Type A blood 50%, Type B 50%, Type AB 0%, Type O Blood 0%

d)

Type A blood 100%

16.

A woman has type B blood and her husband has type O blood. What must be the woman's genotype, if they have a child with type O blood?

a)

Heterozygous B

b)

Homozygous B

c)

Homozygous O

d)

Heterozygous O

17.

Select all that type B can receive from

a)

A

b)

B

c)

AB

d)

O

18.

If a father is heterozygous A and the mother is heterozygous B, what are the possible phenotypes of the offspring?

a)

25% AO

25% AB

25% BO

25% OO

b)

50% A

50% B

c)

25% A

25%AB

25% B

25% O

d)

25% A

25% B

50% O

WaygroundAnswer Key

Blood types

Total questions: 18

1.
b)

Antigens

2.
d)

none

3.
c)

B

4.
a) O
5.
a) O
6.
d)

It doesn’t contain antigen A or antigen B.

7.
b) O-
8.
a) AB+ 
9.
c)

codominance

10.
d) 25%
11.
c) 50%
12.
a) 0%
13.
b) genetics
14.
d) A and B
15.
c)

Type A blood 50%, Type B 50%, Type AB 0%, Type O Blood 0%

16.
a)

Heterozygous B

17.
b)

B

, d)

O

18.
c)

25% A

25%AB

25% B

25% O

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FAQs

What does this blood types worksheet cover?

This Grade 7 worksheet uses 17 multiple-choice questions and 1 multiple-select question to assess blood type antigens and antibodies, ABO and Rh compatibility, codominance, and genetic inheritance. Students identify blood-type features, distinguish universal donor and recipient types, and calculate offspring probabilities from stated parental genotypes.

How can I use this worksheet to teach blood type inheritance?

Introduce the worksheet by reviewing the difference between red blood cell antigens and blood plasma antibodies, then model how ABO genotypes produce phenotypes. Before students complete the inheritance items, have them use a Punnett square for examples such as two heterozygous type A parents or a type O parent with a type AB parent. Use the multiple-choice options to prompt students to explain why each probability is possible or impossible.

What mistakes should I watch for when students complete this blood types worksheet?

Watch for students confusing antigens on red blood cells with antibodies, especially when identifying the antibody associated with type A blood. Students may also select AB as the universal donor or overlook the distinction between O in ABO-only questions and O- when the Rh factor is included. In the inheritance questions, check that they use the stated genotypes, recognize codominance for AB blood, and calculate probabilities rather than assuming every blood type is equally likely.

How do I assign and grade this blood types worksheet?

This worksheet is available as a printable PDF and as a digital quiz on Wayground, and it includes a complete answer key. You can grade printable submissions by scanning student work with the Wayground for Teachers app, or review responses through the digital quiz. The printable version also gives schools an option for reducing screen time.

How does this worksheet help students predict inherited blood types?

The inheritance questions require students to connect parental genotypes with possible child phenotypes and percentage outcomes. By solving crosses involving heterozygous type A parents, AA and AB parents, two AB parents, and type O and AB parents, students practice identifying when type O, type AB, type A, or type B blood is possible or impossible.

Where can I find more worksheets like this on Wayground?

Wayground offers a comprehensive collection of free printable worksheets and practice problems across all subjects, with downloadable PDFs and answer keys to support mastery of essential skills and concepts. Browse more resources at https://wayground.com/en-us/worksheets.

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