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Central Dogma Review

Total questions: 10

Worksheet time: 6mins

Name
Class
Date
1.
Which of the following represents the maximum number of amino acids that could be incorporated into a polypeptide encoded by 21 nucleotides of messenger RNA?
a)
3
b)
7
c)
21
d)
42
2.
During post-translational modification, the polypeptide from a eukaryotic cell typically undergoes substantial alteration that results in 
a)
excision of introns
b)
addition of a poly (A) tail
c)
formation of peptide bonds
d)
a change in the overall conformation of a polypeptide
3.
If a messenger RNA codon is UAC, which of the following would be the complementary anticodon triplet in the transfer RNA?
a)
ATG
b)
AUC
c)
AUG
d)
ATT
4.
DNA replication occurs through a complex series of steps involving several enzymes.  Which of the following represents the correct order beginning with the earliest activity of enzymes involved in DNA replication?
a)
helicase RNA primase, DNA polymerase, ligase, 
b)
DNA polymerase, RNA primase, helicase, ligase
c)
RNA primase, DNA polymerase, ligase, helicase
d)
Helicase, RNA primase, DNA polymerase, ligase
5.
The base composition of DNA varies from one species to another.  Which of the following ratios would you expect to remain constant in the DNA?
a)
Cytosine: Adenine
b)
Pyrimidine: Purine
c)
Adenine: Guanine
d)
Guanine: Deoxyribose
6.
All of the following are differences between prokaryotes and eukaryotes EXCEPT
a)
eukaryotes have linear chromosomes, while prokaryotes have circular chromosomes
b)
eukaryotes pssess double stranded DNA, while prokaryotes possess single stranded DNA
c)
eukaryotes process their mRNA, while in prokaryotes, trascription and translation occur simultaneously
d)
eukaryotes contain membrane bound organelles, while prokaryotes do not
7.
The nucleotide sequence of a DNA molecule is 5'-C-A-T-A-3'.  A mRNA molecule with a complementary codon is transcribed from the DNA in the process of protein synthesis a tRNA pairs with a mRNA codon.  What is the nucleotide sequence of the tRNA anticodon?
a)
5'-G-T-A-3'
b)
5'G-U-A-3'
c)
5'-C-A-U-3'
d)
5'-U-A-C-3'
8.
Which of the following is NOT a characteristic of bacteria?
a)
circular double-stranded DNA
b)
membrane-bound cellular organelles
c)
plasma membrane consisting of lipids and proteins
d)
ribosomes that synthesize polypeptides
9.
Which of the following DNA strands would serve as a template for the amino acid sequence shown above?
a)
3'-ATGCGACCAGCACGT-5'
b)
3'- AUGCCACUAGCACGU-5'
c)
3'-TACGGTGATCGTGCA-5'
d)
3'UACCGGUGAUCGUGCA-5'
10.
The mRNA above was found to be much smaller than the original mRNA synthesized in the nucleus.  This is due to the
a)
addition of a poly(A) tail to the mRNA moleucle
b)
addition of a cap to the mRNA molecule
c)
excision of exons from the mRNA molecule
d)
excision of introns from the mRNA molecule