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NovoMix Quiz 2nd PoA Athena

Total questions: 30

Worksheet time: 15mins

Name
Class
Date
1.

According to Strojec et al, % of HbA1c Red. was ............. % with NovoMix

a)

1.25

b)

1.41

c)

1.6

d)

2.5

2.

According to Guigliano et al meta-analysis , HbA1c% -Weight changes - Hypoglycemia were non significant differ between Premixed insulin and Basal Bolus except insulin dose was ...................

a)

higher with Premixed insulin

b)

lower with Premixed insulin

c)

was not tested

d)

none of the above

3.

According to Davisdon et al meta-analysis , the risk of nocturnal hypoglycemia was lower with NovoMix by ................... vs BHI

a)

55%

b)

50%

c)

45%

d)

none of the above

4.

According to the UKPDS data, 1% reduction in HbA1c was associated by .................... in Stroke

a)

10%

b)

12%

c)

14%

d)

16%

5.

According to OnceMix Trial, once daily of NovoMix was ............................ to once daily glargine

a)

non-inferior

b)

inferior

c)

superior

d)

non-inferior & superior

6.

according to Malek et at, NovoMix OD, Bid & TiD reduce HbA1c% by ................. at the end of the trial.

a)

1.2%

b)

1.4%

c)

1.6%

d)

2.5%

7.

according to Davidson et al meta-analysis, the risk of Major hypoglycaemia was reduced with NovoMix by .................... vs BHI

a)

50%

b)

55%

c)

45%

d)

none of the above

8.

According to Galapagos et al, NovoMix OD or BiD was compared vs Basal +/- Bolus over ...........Type 2 Patients

a)

551

b)

394

c)

934

d)

266

9.

According to Diuezide et at Trial , A Sub-group analysis of A1chieve, % of red. of HbA1c was ...............% with NovoMix After switching from Basal Bolus

a)

1.9

b)

1.8

c)

2.5

d)

1.7

10.

According to Hermansen et al. the design of the trial was randomized controlled ........................ cross over trial between BHI, NovoMix and LisproMix 25

a)

open label

b)

double blind

c)

double dummy

d)

none of the above

11.

according to Velojic et al, after 3 months , % of HbA1c reduction with NovoMix was ...................%.

a)

1.41

b)

2.79

c)

2.5

d)

1.6

12.

According to the SPC of NovoMix , duration of action of NovoMix is up to ..............

a)

18 hours

b)

22 hours

c)

12 hours

d)

24 hours

13.

According to SimpleMix Trial, Switching uncontrolled Pts. on Basal insulin to NovoMix resulted into additional reduction in HbA1c by .................... in the investigator driven titration.

a)

1.2

b)

0.75

c)

0.97

d)

1.6

14.

According to Haddad et al. , Sub -group analysis of A1chieve trail, ....................... were switched to NovoMix for 6 months

a)

oral Pts.

b)

Basal Pts.

c)

BHI Pts.

d)

Basal Bolus Pts.

15.

According to Libel et al Review article, .......................... of experience were studied with NovoMix

a)

12 years

b)

15 years

c)

10 years

d)

none of the above

16.

According to Haddad et al, Sub-group analysis of A1chieve, at the end of the trial, % of red. in HbA1c with NovoMix was .......................

a)

1.7%

b)

1.8%

c)

1.9%

d)

2.5%

17.

According to Naggar et al, Sub-group analysis of A1chieve, at the end of the trial, % of red. in HbA1c with NovoMix was .......................

a)

1.7%

b)

1.6%

c)

1.8%

d)

none of the above

18.

According to S. Linjawi et al. , step wise approach between NovoMix and Basal Bolus regimens resulted into ................ of Hypoglycaemia with NovoMix OD, BID and TID vs Basal Bolus

a)

more risk

b)

less risk

c)

similar risk

d)

Non reported

19.

According to S. Linjawi et al. , step wise approach between NovoMix and Basal Bolus regimens resulted into ................ weight gain with NovoMix OD, BID and TID vs Basal Bolus

a)

more

b)

less

c)

compareble

d)

none reported

20.

According to Garber et al trial, % of Pt's achieve HbA1c goal less than 7% with OD, BID and TID were .......................

a)

41%-60%-77%

b)

21%-70%-77%

c)

41%-60%-70%

d)

41%-70%-77%

21.

According to Raskin et al, NovoMix BID resulted into more reduction in HbA1c% by ................... vs Basal Oral

a)

2.36%

b)

2.79%

c)

2.5%

d)

1.41%

22.

According to Galapagos trial , % of Pts. Achieve the goal of HbA1c less than 7% were .......................

a)

65%

b)

40%

c)

52%

d)

2%

23.

According to the Blood glucose level , the Impaired fasting glucose level is between ..................................

a)

110-125 mg/dl

b)

100-125 mg/dl

c)

140-199 mg/dl

d)

90-125 mg/dl

24.

According to the Garber et al, with OD, BID and TID adm. of NovoMix, at the end of the trial , HbA1c was reduced by ..................

a)

2.2%

b)

2%

c)

1.9%

d)

2.5%

25.

According to Raskin et al trial, NovoMix BID vs Basal oral resulted into more Pts. Achieve HbA1c goals either less than 7% by ..................or 6.5% by ........................

a)

41% - 20%

b)

60%-40%

c)

66%-42%

d)

none of the above

26.

According to S. Linjawi et al, ............... Pts of type 2 were randomized into NovoMix OD, BID & TID vs Basal Bolus for ........................ weeks

a)

440 pts. - 40 weeks

b)

335 pts. - 32 weeks

c)

551 pts. - 50 weeks

d)

None of the above

27.

According to Hermansen et al, Glucose excursion level between 0-5 hours was lower with NovoMix vs BHI by ............... and vs lisproMix 25 by ............

a)

10% - 17%

b)

12%-19%

c)

17%-10%

d)

none of the above

28.

According to Libel et al. review article, NovoMix across 15 years of experience have shown to be .................. , .................... & .................. in initiation or intensification options

a)

safe

b)

effective

c)

simple to use

29.

According to Galapagos et al trail, in addition to NovoMix OD or BiD being more effective in reducing the HbA1c% vs Basal +/- Bolus , the risk of severe hypoglycemia was ................. with NovoMix vs basal plus

a)

lower

b)

higher

c)

simillar

d)

none of the above

30.

from the Acute diabetes complications ............ &...............

a)

Retinopathy

b)

DKA

c)

Nephropathy

d)

Myocardial infarctian

e)

Hypoglycemia