A 30-year-old woman with a past medical history of type 1 diabetes comes to the emergency room with a productive cough, fever, and polyuria for 4 days and progressive lethargy and confusion for the last day. She complains of abdominal pain and nausea with vomiting. Her breath smells fruity, her serum glucose is 600 mg/dL, and her serum potassium is 5.1 mEq/L. Initial management of this patient will likely include IV fluids, insulin, and which of the following?

A 53-year-old man comes to the office because of numbness and paresthesias at the ends of his fingers on both hands for 4 months. At night, this sensation sometimes worsens to a burning pain. He says he has also had blurred vision, weight loss, and frustrating impotence during the last 2 months. He has decided to leave his career due to these functionally disabling limitations. Examination shows decreased sensation of the affected extremities. Which of the following enzymes is the most likely involved in the underlying cause of his neurological complaints?

A 14-year-old boy comes to the emergency department with his parents because they found him unconscious 10 minutes ago. They say that he has recently been very fatigued and has constantly been complaining of hunger and has been drinking a lot more water than usual. Laboratory studies show undetectable C-peptide and a very high concentration of another molecule. Which of the following most likely uses a high-affinity, hormone-independent transporter to uptake this molecule?

A 24 year old female with a history of type 1 diabetes mellitus presents with weakness, lightheadedness, dyspnea, and confusion.

VITAL SIGNS ARE:

Pulse 125

BP: 92/62 mmHg

RR: 32 per min

Glucose: 300

Which of the following is most likely to be found:

Increase flux through the polyol pathway consumes ______ which then leads to ________ and lead to cellular injury.

A patient with jaundice was diagnosed with cancer of the head of the pancreas. Which structure was compressed by the tumor?

An islet prepared with a modified aldehyde fuchsin stain shows the cells deep brownish purple cells in the periphery produce_________ while the centrally located brownish orange cells produce________

Identify structure B and the major substances excreted via this structure?

The following proccess is an autoimmune process mediated by _______ that infiltrate the islets and attack the _________

Step A in this pathway involves an influx of _________ in __________ which ultimately leads to the "B labeled step" which is ______ release into systemic circulation.

_______ is your favorite person ever in SIGS and you cannot wait for him to be leader.