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PHAR 104 Final Exam Practice

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Antifungals can be dispensed in which of the following forms?

a)

oral

b)

topical

c)

injectable

d)

all of the above

2.

ASA and NSAID’s are associated with gastric ulcers by inhibiting which of the following:

a)

prostaglandins

b)

leukotrienes

c)

bradykinin

d)

histamine

3.

Which of the following doses has 100% bioavailability?

a)

1 tablet PO

b)

1 mL PO

c)

1 supp pr

d)

2 mL IV

4.

What effect of antihistamine use is intensified with alcohol consumption?

a)

Hyperactivity

b)

Constipation

c)

Sedation

d)

Dry mouth

5.

Nephrotoxic drugs:

a)

damage the liver

b)

damage the kidneys

c)

cause cancer

d)

cause birth defects

6.

Why would antihistamines be prescribed to help treat vertigo?

a)

To decrease the production of fluid in the ear reducing the chances of vertigo

b)

To increase the drainage of fluid in the ear

c)

To reduce natural sympathetic symptoms of vertigo

d)

To help moderate cholinergic symptoms of vertigo

7.

Two issues that determine the degree to which a drug is bound to a protein site are:

a)

efficacy and bioavailability

b)

affinity and number of available sites on cells

c)

bioavailability and the number of T-cells

d)

absorption and evaporation

8.

How do salicylates increase the risk of PUD?

a)

Salicylates interfere with the formation of acid, reducing enzymes in the GI tract.

b)

Salicylates block prostaglandins from forming, reducing the protective mucosal lining of the GI tract.

c)

Salicylates increase production of histamine in the stomach, increasing acid in the GI tract.

d)

Salicylates contain an enzyme that H. pylori feed on, increasing bacteria in the gastrointestinal (GI) tract.

9.

Why is it important not to switch manufacturers of theophylline once a patient has established a good drug response to it?

a)

The coloring used by different manufacturers has shown to increase side effects in some patients.

b)

The half-life for theophylline varies greatly from manufacturer to manufacturer, so dosing may need to be adjusted.

c)

The additives from the various manufacturers have shown to increase hypersensitivity to the drug.

d)

The bioavailability differs from manufacturer to manufacturer.

10.

H1 receptors in the upper respiratory system are blocked by

a)

antihistamines

b)

H2 receptors

c)

histamine

d)

decongestants

11.

Why is it important to include the following warning label on corticosteroid inhalation treatment: “Rinse mouth thoroughly after use”?

a)

Rinsing will reduce the chance of drug contamination.

b)

A residue is left behind after each inhalation, potentially causing an infection.

c)

The pH change in the mouth after rinsing helps increase absorption of the drug.

d)

Rinsing helps keep the mouth minty fresh.

12.

Duration of action is the time between the _____ of action and _____ of drug action.

a)

duration, concentration

b)

onset, mechanism

c)

onset, discontinuation

d)

mechanism, duration

13.

The temperature that must be maintained for an uninterrupted cold chain from the manufacturer to its final destination is _____.

a)

59° to 86° F

b)

2° to 8° C

c)

2° to 6° F

d)

32° to 59° C

14.

Which of the following may occur when taking an anticholinergic for IBS?

a)

Vomiting

b)

Diarrhea

c)

Dry mouth

d)

Urinary incontinence

15.

Which type of drug suppresses cough?

a)

Antihistamine

b)

Antiemetic

c)

Decongestant

d)

Antitussive