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Renal Physiology

Total questions: 25

Worksheet time: 13mins

Name
Class
Date
1.

Normal renal blood flow is:

a)

0.2 - 0.5 L/min

b)

0.5 - 1.0 L/min

c)

1.0 - 1.5 L/min

d)

1.5 - 2.0 L/min

e)

2.0 - 2.5 L/min

2.

Normal effective renal plasma flow is approximately:

a)

300 ml/min

b)

600 ml/min

c)

900 ml/min

d)

1200 ml/min

e)

1500 ml/min

3.

There is a sharp fall in glomerular filtration rate as the mean arterial blood pressure drops below:

a)

60 mmHg

b)

70 mmHg

c)

80 mmHg

d)

90 mmHg

e)

100 mmHg

4.

The following causes decreased renal blood flow EXCEPT:

a)

High protein diet

b)

Sympathetic stimulation

c)

Angiotensin II

d)

Noradrenaline

e)

Exercise

5.

Which of the following statement is correct?

a)

Renal cortex has low renal blood flow

b)

Renal cortex has high O2 extraction

c)

Renal medulla has high renal blood flow

d)

Renal medulla has low O2 extraction

6.

Renal blood flow is kept constant by autoregulation in the mean systemic blood pressure range of:

a)

0 - 90 mmHg

b)

90 - 200 mmHg

c)

200 - 250 mmHg

7.

Normal glomerular filtration rate is:

a)

25 ml/min

b)

50 ml/min

c)

100 ml/min

d)

125 ml/min

e)

200 ml/min

8.

Filtration fraction is:

a)

GFR / RPF

b)

Cr CI / RPF

c)

([Cr]urine / [Cr]plasma) x urine flow rate

d)

RPF / GFR

9.

Which of the following will be most effectively filtered at the glomeruli:

a)

Neutral substance with diameter 10 nm

b)

Neutral substance with diameter 4 nm

c)

Cationic substance with diameter 4 nm

d)

Anionic substance with diameter 4 nm

e)

Cationic substance with diameter 7 nm

10.

Which of the following substance are secreted by renal tubules:

a)

Sodium

b)

Potassium

c)

Chloride

d)

Bicarbonate

e)

Urea

11.

Glucose is reabsorbed from proximal convoluted tubule using:

a)

Passive diffusion

b)

Endocytosis

c)

Facilitated diffusion

d)

Secondary active transport

e)

Primary active transport

12.

Most of the filtered water is reabsorbed in:

a)

Proximal convoluted tubule

b)

Descending loop of Henle

c)

Ascending loop of Henle

d)

Distal convoluted tubule

e)

Collecting duct

13.

Which of the following statement is FALSE:

a)

Thick ascending limb of loop of Henle has Na/K/CI active transport.

b)

Thin descending limb of loop of Henle is highly permeable to water.

c)

Osmolality is greatest at the tip of loop of Henle.

d)

Water diffuse out of blood vessel from the ascending limb of vasa recta into its descending limb.

e)

Thin ascending limb of loop of Henle is impermeable to water.

14.

The following parts of the nephron is permeable to urea:

a)

Descending limb of loop of Henle

b)

Ascending limb of loop of Henle

c)

Distal convoluted tubule

d)

Collecting ducts

15.

Movement of urea in collecting duct is facilitated by:

a)

Noradrenaline

b)

Dopamine

c)

Vasopressin

d)

Angiotensin II

16.

Maximal urine output that can be produced by water diuresis is:

a)

125 ml/min

b)

16 ml/min

c)

160 ml/min

d)

1.6 L/day

e)

16 L/day

17.

The following substance lead to increased sodium reabsorption in kidney:

a)

Aldosterone

b)

Vasopressin

c)

ANP

d)

PGE2

18.

In the kidney, potassium secretion occurs in:

a)

Proximal convoluted tubule

b)

Loop of Henle

c)

Distal convoluted tubule

d)

Collecting ducts

e)

Potassium is not secreted into renal tubules

19.

Which of the following diuretics act on the proximal convoluted tubule:

a)

Acetazolamide

b)

Frusemide

c)

Chlorthiazide

d)

Mannitol

e)

Amiloride

20.

Which of the following injury will lead to a large volume, hypotonic bladder?

a)

Transection of afferent pelvic nerve from bladder

b)

Transection of both afferent pelvic nerve & efferent parasympathetic nerve to bladder

c)

Transection of brainstem above midbrain

d)

Transection of brainstem above pons

21.

Which of the following is NOT an extracellular buffer system?

a)

Carbonic acid-bicarbonate system

b)

Dibasic phosphate system

c)

Plasma protein

d)

Hemoglobin (Histidine residues)

22.

Hydrogen ion is NOT secreted in the following part of the nephron:

a)

Proximal convoluted tubule

b)

Loop of Henle

c)

Distal convoluted tubule

d)

Collecting ducts

23.

Hydrogen ion secretion in proximal convoluted tubule uses:

a)

Passive diffusion

b)

Proton pump

c)

H+/K+ exchange

d)

H+/Na+ exchange

24.

In the renal tubules, bicarbonate is responsible for buffering hydrogen ion in:

a)

Proximal convoluted tubule

b)

Loop of Henle

c)

Distal convoluted tubule

d)

Collecting ducts

25.

Normal anion gap is approximately:

a)

0 mmol/L

b)

1-5 mmol/L

c)

5 - 10 mmol/L

d)

10 - 15 mmol/L

e)

15 - 20 mmol/L

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