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Total questions: 26
Worksheet time: 13mins
Which of the ff statements is false?
Hormone deficiency is often diagnosed with hormone challenge tests
Hormonal excess is diagnosed with suppression tests
Posterior pituitary hormones include vasopressin and Prolactin
The HPT axis is the primary regulator of thyroid function
The most common cause of endocrine abnormalities arising from prenatal period is the TORCHS syndrome. Which among the ff. etiologic agents was added?
Zika virus
HIV
EBV
Smallpox
This is the tricky period of postnatal insult during pediatric development
Period of exclusive breastfeeding (1st six months)
Complementary feeding (6 months onwards)
Preschool age
Toddler stage
What is the expected increase in length during the 1st year of an infant?
25cm
23cm
20cm
28cm
A child manifesting with short stature, vomiting, bitemporal hemianopsia and increaded urination is most likely experiencing:
Infratentorial tumor
Supratentorial tumor
Hypothalamic tumor
Pseudotumor cerebri
The ff. are criteria for growth failure, except:
Height below the 10th percentile of age & sex
Height >2 SD below sex adjusted mid parental height
Absent or low levels of GH
None of the above
A child, apparently normal upon delivery,was suffering from untreated nephrotic syndrome and severe malnutrition. He most likely will develop?
Postnatal pathologic stature
constitutional growth delay
Familial short stature
Prenatal onset pathologic short stature
A 16 year old male that you have been handling since birth as a pediatrician has been growing below the mean for the most time except that there is a spurt for the past 2 years and he is expected to reach the mean height in 1-2 years time. The child most likely has:
Postnatal pathologic stature
Constitutional growth delay
Prenatal onset pathologic stature
Familial short stature
R.R. a 15 year old female consulted to you because of her short stature. You noted she has webbed neck, widely spaced nipples,primary amenorrhea, and a heart murmur. You will request for which test to determine the diagnosis?
Serum IGF to test for hyypopituitarism
Cranial CT to determine the cause of hypopituitarism
Genetic and karyotype testing
2D echo to determine heart pathology that has caused the manifestations
What test is used to determine the bone age of a patient?
DEXA
AP Xray of the left wrist
AP Xray of the right wrist
AP Xray of the left arm
What is the diagnostic test to determine GH levels?
Serum GH test
Serum IGF-1
Serum GHRH
None of the above
Which of the ff statements are true regarding GH therapy
0.18-0.30 mg/kg/wk IM in 6-7 divided doses of hGH is given
Stop treatment if growth rate is <1cm / year
Bone age for girls is greater than 14 years
Bone age for boys is greater than 17 years
The ff are are true regarding hyperpituitarism, except:
Gigantism occurs with excessive GH before bone closure
Acromegaly occurs with excessive GH after bone closure
All parts are enlarged in acromegaly
The tests to be considered for GH excess are serum IGF-1 and Cranial CT
Diabetes insipidus can be clinically differentiated from diabetes mellitus due to the lack of:
polydipsia (2L/m2/24hr)
polyphagia
polyuria
Fluid restriction test for 12 hours
J.M., a 14 year old female, consulted to you due to a possible diabetes insipidus. 12 hour water deprivation test resulted to urine SG of 1.005. Vasopressin administration resulted to SG of 1.030. What is the most likely diagnosis?
nephorgenic DI
SIADH
Central DI
Psychogenic polydipsia
Which of the ff is true of precocious puberty?
Before 9 years old in girls
Before 9 years old in boys
first physical sign is pubarche
First clinical sign is growth spurt
What is compound associated with exophthalmos in patients with Graves disease
glycosaminoglycans
protamine sulfate formation
Reactive oxygen species
Caspace 9
Acute life threatening condition due to excessive thyroid hormone production
Thyroid storm
Myxedema coma
Riedel's thyroiditis
Fabry's disease
What diagnostic test is used to confirm Graves disease
TRAb
serum TSH
Serum free T4 and T3
Serum thyroglobulin
A 17 year old female had already have 4 recurrent hyperthyroid episodes due to Graves disease. What definitive treatment would you recommend?
Radioiodine ablation
Thyroidectomy
Retitrate methimazole medication
Retitrate PTU medication
Why is PTU the drug of choice for pregnant mothers?
Has added benefit of blocking peripheral conversion of T4 to T3
Wider therapeutic index
Less able to cross the placenta
Shorter serum half life compared to methimazole
The ff are features of congenital hypothyroidism, except:
All aspects of development are delayed
Birthweight and length are normal
Prolonged physiologic jaundice
Frequent diarrhea
Most common cause of thyroid disease in children and adolescents
Graves disease
Hashimoto's thyroiditis
Congenital hypothyroidism
Goiter
Positivity for thyroid peroxidase antibodies is seen in 90% of children in this condition:
Graves disease
Hashimoto's thyroiditis
Kawasaki disease
Riedel's thyroiditis
A 14 year old female underwent thyroid scan for suspected thyroid pathology. Scan revealed irregular and patchy distribution of radioisotope. The condition is most probably be:
Thyroiditis
Multinodular goiter
Graves disease
Thyroid cyst
The ff statements are true for thyroid gland, except:
The recommended daily intake of iodine for infants is >30ug/kg/day
Treatment for Hashimoto's thyroiditis is Levothyroxine 50-150ug/day
Congenital hypothyroid babies usually has respiratory difficulties due to large tongue
Seldom do patients with graves disease are found euthyroid and asymptomatic
