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3.5 IB Biotech Roundup

Total questions: 25

Worksheet time: 2hrs 43mins

Name
Class
Date
1.

What is the purpose of PCR?

a)

To produce millions of copies of the DNA genome

b)

To produce millions of copies of a specific region of DNA

c)

To add nucleotides to a DNA sequence

d)

To watch polymerase work.

2.

What is the function of a primer?

a)

To identify the particular region of DNA to be copied by PCR.

b)

To copy DNA.

c)

To create DNA nucleotides.

d)

To maintain the temperature of the PCR reaction.

3.

From where does Taq polymerase come?

a)

Bacteria that live in hydrothermal vents/hot springs.

b)

Pig cells

c)

The rain forest

d)

The CDC

4.

What are the uses of PCR?

a)

Cloning

b)

Paternity Testing

c)

Genotyping

d)

DNA Profiling

5.

A special protein that targets a specific base sequence and cuts DNA into smaller fragments.

a)

PCR

b)

DNA Polymerase

c)

Helicase

d)

Restriction Enzyme

6.

What is the term given to symmetrical ends of DNA after being cut by a restriction enzyme?

a)

Blunt Ends

b)

Sticky Ends

c)

Ligated Ends

d)

Restrictive Ends

7.

The recognition sites for restriction enzymes are usually...

a)

alliterations

b)

pallindromes

c)

acronyms

d)

analogies

8.

Restriction Enzymes were primarily used as....

a)

defense by protozoa against antibiotics

b)

tools by viruses to cleave bacterial genome

c)

defense by bacteria against bacteriophages viruses

d)

tools to cleave DNA during replication

9.

Which restriction enzymes from above make blunt cuts? (2)

a)

Alul

b)

HaeIII

c)

BamHI

d)

HindIII

e)

EcoRI

10.

Another name for a restriction enzyme is...

a)

an endonuclease

b)

an extremophile

c)

Taq polymerase

d)

a pallindromic ligase

11.

What is a plasmid?

a)

Chloroplast DNA

b)

Mitochondrial DNA

c)

A bacterial chromosome

d)

Small circle of DNA that can transfer genes to or from a prokaryote

12.

Why do the fragments of DNA in gel electrophoresis travel away from the negative electrode?

a)

DNA is negatively charged so attracted to the positive end of the unit

b)

DNA is positively charged so is attracted to the negative end of the unit

c)

the agarose gel is negatively charged

d)

the agarose gel is positively charged

13.

In gel electrophoresis, the largest DNA fragment will appear....

a)

closest to the starting wells

b)

farthest from the starting wells

c)

three quarters away from the starting wells

d)

it depends on how many fragments there are

14.

Gel electrophoresis enables scientists to.....

a)

separate DNA fragments.

b)

combine DNA fragments.

c)

count the genes in DNA

d)

insert DNA in cells

15.

How many restriction sites are there on this plasmid for the endonucluease BamHI?

a)

1

b)

2

c)

3

d)

4

16.

Which is happening during stage 'A'?

a)

The DNA sample is being amplified using a polymerase chain reaction

b)

The DNA sample is being cut into fragments using a restriction enzyme

c)

The DNA sample is being amplified using restriction enzymes

d)

The DNA sample is being cut into fragments using a polymerase chain reaction

17.

When Dolly the Sheep was cloned, what type of cell was taken from the adult sheep that she was cloned from?

a)

Gamete

b)

Egg

c)

Somatic

d)

Sperm

18.

Which of the following is not true about clones and cloning?

a)

Clones are two organisms with identical DNA.

b)

Clones can happen naturally

c)

Clones can be made in labs

d)

Only maternal twins are clones

e)

Clones do not live as long as non-clones

19.

What happens during somatic cell nuclear transfer (SCNT)?

a)

An organism is naturally cloned

b)

The DNA in a somatic cell is placed into an egg cell

c)

The DNA of an egg cell is placed into a somatic cell

d)

An organisms does sexual reproduction

20.

Fact or myth: Cloning can happen in nature.

a)

Fact

b)

Myth

21.

What is natural cloning?

a)

When scientists insert the the DNA of a somatic cell into a nucleus free egg cell

b)

A natural form of reproduction that has allowed life forms such as bacteria to survive

c)

When a mother is carrying paternal twins during pregnancy

d)

Cultivating a population of cells from a single cell.

22.

All offspring of asexual reproduction are identical

a)

True

b)

False

23.

Bacteria reproduce asexually by a process called

a)

replication

b)

meiosis

c)

mitosis

d)

binary fission

24.

Which is not a GMO?

a)

A genetically modified organism

b)

An organism with altered DNA

c)

An organism developed by scientists to have desired traits

d)

An organism that has identical DNA to it's parent

25.

What is a major difference between a somatic cell and an egg cell?

a)

Somatic cells are halpoid (23 chromosomes), egg cells are diploid (46 chromosomes)

b)

Egg cells are halpoid (23 chromosomes), somatic cells are diploid (46 chromosomes)

c)

Somatic cells can divide, egg cells cannot

d)

Egg cells have DNA in their nucleus, somatic cells do not