WorksheetsBME 221 F2019 Exam 1 Review
Total questions: 10
Worksheet time: 30mins
All of the following are true of "melting" or "denaturing" DNA during PCR EXCEPT?
The hydrogen bonds are disrupted
The phosphodiester linkage is disrupted
The double helical structure is lost
Occurs as a result of temperature changes
All of these are true
The critical micelle concentration refers to
The minimum concentration of lipid molecules required to form micelles
The maximum concentration of lipid molecules required to form micelles
The minimum concentration of lipid molecules soluble in a polar solvent
The concentration above which micelles can no longer form
The concentration above which multilamellar vesicles form over unilamellar ones
Common secondary structures are energetically favored because
A. They optimize the backbone hydrogen bonds
B. They optimize the adjacent residue hydrogen bonds
C. They minimize clashes between adjacent groups
D. A and C
E. A, B, and C
In a conservative substitution or replacement
A frame shift has occurred leading to a new amino acid
A large segment of DNA was deleted
The new amino acid has similar biochemical properties to the original
The new amino acid has different biochemical properties to the original
The protein is exactly the same
Which of the following statements about alpha helices is FALSE?
The helix is typically right handed
Each residue in the helix creates a 100 degree turn of the helix
The backbone atoms are in the core of the helix
The helix has an overall macrodipole, where the C-terminal is partially positively charged and the N-terminal is partially negatively charged
The hydrogen bonds holding the helix together are parallel to the helix axis
Because some proteins fold with the assistance of molecular chaperones, the thermodynamic hypothesis does not apply to these proteins.
TRUE
FALSE
All proteins have quaternary structure.
TRUE
FALSE
A likelihood ratio of 1 indicates that the probability of the ith amino acid being replaced by the jth amino acid is the same as due to random chance.
TRUE
FALSE
Protein tertiary structure is generally more highly conserved than the primary structure.
TRUE
FALSE
Of the following 15-base pair double stranded DNA sequences (note: only one strand is shown), which will be MOST stable at higher temperatures.
CCCGCATCGCCATCG
CATCCTAGCGACTAT
AAATGCATACATCTT
CGCTTATCGCCATAA
