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SIO3008 Fungal Biotechnology (Fungal Drugs 1)

Total questions: 10

Worksheet time: 6mins

Name
Class
Date
1.

What is NOT the advantages of microbial systems as drug models

a)

Microbes are cheaper than laboratory animals

b)

Simple repetitive process

c)

Easier detection

d)

Easy to scale-up

e)

Screening require small number of strains

2.

Which one describes the use of microbes to mimic the mammalian drug metabolism?

a)

Anabolic steroid --- Male human urine

b)

Pregnant mares --- Testosterone

c)

CNS stimulant --- Artemisinin

d)

Penicillum notatum ---- Progesterone

e)

Chlorella sp. ----- Artemisinin

3.

What is NOT in 5 Amazing Components of Ganoderma lucidum?

a)

Vitamins

b)

Polysaccharide

c)

Ganoderic essence

d)

Triterpenoid

e)

Adenosine

4.

What is SLF?

a)

Solid-liquid fermentation

b)

Submerged-liquid fermentation

c)

Sustainable-liquid fermentation

d)

Sucrose-liquid fermentation

e)

Substrate-liquid fermentation

5.

What is the disadvantage of growing Ganoderma lucidum in liquid fermentation?

a)

Short cultivation time

b)

Easy for extractions

c)

Lower biomass than the solid fermentation

d)

Consistent quality than the solid fermentation

e)

Cheaper and can be produced in bulk

6.

Define UPSTREAM in Ganoderma lucidum liquid fermentation?

a)

Fruiting bodies ---- Shake flask fermentation ---- Mycelial pellets

b)

Mycelial mat on agar ---- Shake flask fermentation --- Mycelial pellets

c)

Mycelial pellets ---- EPS precipitation ---- Beta-glucan

d)

EPS ------ dialysis ------ Beta-glucan

e)

Does not require production procedure

7.

Choose the correct order of DOWNSTREAM in Ganoderma liquid fermentation?

a)

Mycelial pellets ----- EPS precipitation ------- Beta---glucan

b)

Mycelial pellets ------ Dialysis ------ EPS precipitation

c)

Mycelial pellets ------ Beta-glucan ------ Dialysis

d)

Mycelial pellets ------ Beta-glucan ------- EPS precipitation

e)

Mycelial pellets ------ Dialysis ----- EPS precipitation ---- Beta-glucan

8.

Bulletin of the World Health Organisation has stated....

a)

Inability to treat diarrhoea

b)

Antimicrobial drug resistance

c)

Shortages of medicines

d)

We need more chemotherapy pills

e)

The last year of new antibacterials approved for human use is 1987

9.

What is AMR?

a)

Anti-multidrug resistance

b)

Antimicrobial resistance

c)

Antibiotics resistance

d)

Antidote resistance

e)

Acute-medicine resistance

10.

What is the name of started culture in Tempeh production?

a)

Aspergillus oyrzae

b)

Rhizopus oligosporus

c)

Saccharomyces cerevisiae

d)

Aspergillus oligosporus

e)

Rhizopus oryzae

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