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Viral Life Cycle

Total questions: 10

Worksheet time: 10mins

Name
Class
Date
1.

The Viral Life Cycle has 7 steps. They form the acronym:

a)

AMFAR

b)

EGOT

c)

AFRI-TAB

2.

HIV is a __________________ meaning that it is composed not of DNA but of RNA.

a)

Ebolavirus

b)

Computer Virus

c)

Retrovirus

3.

HIV infects a variety of cells but its main target is the __________________

a)

CDC Cells

b)

Mobile Cell

c)

CD4 T-Cell

4.

Happens when HIV connects and attaches to receptors on the CD4 T-cell.

a)

Integration

b)

Budding

c)

Attachment

d)

Fusion

5.

HIV binds to a CD4+ surface receptor. The HIV virus that contains the RNA and reverse transcriptase enzyme dumps its contents into the host CD4-T cell. This is called ___________________.

a)

Transcription

b)

Reverse Transcription

c)

Attachment

d)

Fusion

6.

HIV infects the CD4 T-Cell DNA through a process called _____________________________________ where the enzyme reverse transcriptase makes a DNA copy of the HIV’s RNA by turning the HIV-RNA into double-stranded DNA within the CD4 T-cell.

a)

Fusion

b)

Reverse Transcription

c)

Assembly

d)

Transcription

7.

Once HIV-DNA is formed, it hides itself in the human DNA inside of the CD4 T-cell nucleus. Another viral enzyme called integrase helps to hides the HIV-DNA into the CD4 T-cell’s DNA. This step is called _______________________.

a)

Integration

b)

Attachment

c)

Transcription

d)

Retrovirus

8.

HIV directs the CD4 T-cell to produce long chains of HIV proteins. Messengers called mRNA carry instructions to a kind of workshop in the cell. As each mRNA strand is processed, a corresponding string of HIV protein is made until new viral proteins are made to form a new HIV. This step is called _____________________________.

a)

Fusion

b)

Transcription

c)

CD4 T-cell

d)

Reverse Transcription

9.

Long strings of proteins are cut up by a viral enzyme called protease into smaller proteins. Protease combines the DNA packages to create new, active HIV. This step is called ______________________.

a)

Budding

b)

Transcription

c)

Integration

d)

Assembly

10.

New HIV is formed which then pushes itself out of the CD4 T-cell. The virus then steals part of the CD4 T-cell protective coating. The virus is able to infect new cells with HIV and cause the number of copies of HIV (Viral Load) to replicate very fast! This is called ___________________

a)

Attachment

b)

Transcription

c)

Budding

d)

Assembly