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WorksheetsDNA replication General Biology
Total questions: 14
Worksheet time: 28mins
Above is a diagram of DNA replication. If this cell were cancerous, a doctor might be using a chemotherapy drug to prevent the replication process from taking place. One such drug, topotecan, inhibits the topoisomerase enzyme from working.
Based on the model, if topotecan is used, how will this affect the replication process?
The hydrogen bonds between the bases will not break
The double helix of the DNA molecule will not unwind
It will prevent the addition of complementary nitrogen bases to the leading or lagging strands
It will prevent the addition of nitrogen bases due to instability of the single stranded DNA chains.
The diagram represents a portion of an organic molecule.
According to the diagram, what can be concluded about this molecule?
The molecule is a long chain composed of smaller units; therefore, it must be a chain of fatty acids
The molecule contains four different nitrogen bases; therefore it must be RNA
The molecule contains the nitrogen base thymine; therefore, it must be DNA
The molecule is composed of sugars and phosphates; therefore, it must be a molecule of ATP
The chemo drug, represented by spheres, is attacking a molecule of biological importance inside a cell. Which statement best describes the drug's method of attack?
The drug is attacking a protein molecule, breaking the peptide bonds between the amino acids
The drug is attacking a protein molecule, breaking the bonds between the carbons and nitrogens in amino acids
The drug is attacking a DNA molecule, breaking the hydrogen bonds between the nitrogen bases.
The drug is attacking a DNA molecule, breaking the covalent bonds between the sugar and phosphate groups.
What happens to the DNA helix when a cell reproduces?
It partially dissolves in the cytoplasm
It unzips and makes a copy of itself
It forms a vesicle until division is complete
It forms a plasmid and doubles in size
What is the relationship between proteins and nucleic acids(NA)?
NAs encode and transmit genetic information which is used to make proteins.
Proteins are produced by the mitochondria that are made up of NAs
Proteins compose the NAs that store genetic information
NAs are the basic units that compose proteins in the cell
A scientist discovered a new organism in a rainforest. She is studying the DNA of the organism to find its similarity to other organisms.
What nucleotides will be present in the DNA sequence of the newly discovered organism?
A,T,C,G
A,U,C,G
G,C,U,T
G,U,A,T
The analysis of a DNA molecule reveals that 30% of its nucleotides are adenine. What percentage of the same DNA molecule would be expected to be guanine nucleotides?
20%
30%
40%
60%
What is the segment of DNA that contains information to synthesize a specific protein molecule?
Chromosome
Codon
Gene
RNA
Identify the complementary DNA strand to the following:
5' ATT TGC CCC 3'
3' UAA ACG GGG 3'
3' UAA ACG GGG 5'
3' TAA ACG GGG 5'
5'TAA ACG GGG 3'
How many hydrogen bonds hold adenine and thymine together?
2
3
1
5
How many hydrogen bonds hold cytosine and guanine together?
2
3
1
5
A nucleotide in DNA consists of what
a sugar phosphate backbone and nitrogenous bases
a sugar, a phosphate, and a nitrogen
adenine, thymine, guanine, cytosine
a sugar and a phosphate molecule
Which of the following is true about DNA?
The nitrogenous bases are connected to the sugar in the sugar phosphate backbone
DNA strands run antiparallel to each other, meaning that one strand runs in a 5' to 3' direction while the other runs in a 3' to 5' direction
DNA replication is semi conservative, meaning that there is one new strand and one original in the final DNA product
DNA replication occurs during mitosis and meiosis during prophase and prophase 1
Which statement best described the image above?
The 5' to 3' strand would be the lagging strand and the 3' to 5' strand would be the leading
The 5' to 3' strand would be the leading strand and the 3' to 5' strand would be the lagging
There is no way to know which strand is the leading or lagging strand without Okazaki fragments being present
The arrows on the image point towards the direction in which DNA replication would take place on each respective strand
