WorksheetsQuiz 5 (Smart Biomaterials, Drug Delivery)
Total questions: 10
Worksheet time: 20mins
Diffusion is a classical drug delivery mechanism
True
False
Dissolution (i.e. Degradation and/or Erosion) is a classical drug delivery mechanism
True
False
Compare the use of biopolymers in transdermal drug delivery systems to synthetic polymers. Which advantages do biopolymers have (compared to synthetic polymers)? Multiple correct answers are possible
Likely higher biocompatibility
Likely cheaper
Likely more mechanically stable
Likely safer
Nitinol is a smart biomaterial. To which class of biomaterials does it belong?
Ceramics
Polymers
Metals
Which aspect about the transition temperature of pNIPAM makes it so interesting as a smart biomaterial for biomedical applications? One correct anwers
It allows for minimal-invasive injection into the body
It enables autoclaving at 121°C
It ensures that pNIPAM does not have to be refridgerated during storage
In what sense is Nitinol "smart"? One correct answer
pH-sensitive
Memory shape
Glucose sensitive
Which statements about this figure are correct? Several answers may be correct.
It shows the use of the pH sensitive biopolymer collagen
It is an alternative to the classical method of cell harvest, which is via trypsin
The main advantage compared to trypsin is less cell damage
It can be used to harvest entire cell sheets for regenerative medicine
From the following statements, pick the most relevant one: Smart biomaterials
Know where to go in the body
Respond to specific changes in the environment
Promote cell growth
Which is the following statements about smart hydrogels are correct? Several correct answers are possible.
Smart hydrogels......
....typically belong to the group of chemically crosslinked hydrogels
....are often used for drug delivery
....typcially belong to the group of physically crosslinked hydrogels
....undergo so-called phase separation (= sol-gel transition) upon exposure to a specific stimuli
Which statement about light-responsive biomaterials is NOT correct? One correct answer.
Photocleavable biomaterials are often used for drug delivery
Light-responsive biomaterials change their properties in response to light of a certain wavelength and intensity, for example UV light
Photocleavable biomaterials are mostly used for diseases that are systemic, i.e. not localized in a specific area of the body
