WorksheetsQuiz 1 - Kinetics
Total questions: 15
Worksheet time: 8mins
It is defined as the manner in which the drug is administered in suitable doses by suitable route with sufficient frequency.
Dosage regimen
Multiple dosage regimen
Dosing ratio
Loading dose
A parameter of dosage regimen which refers to the time interval between doses.
Loading dose
Plasma concentration
Maintenance dose
Dosing frequency
This dose is given to maintain the steady state of drug concentration or reach a plateau.
First dose
Loading dose
Maintenance dose
Continuous dose
When the ratio of loading dose to maintenance dose is less than the half-life, the dose ratio is ____________.
Greater than 2.0
Less than 2.0
Equal to 2.0
AOTA
When the drug reaches steady state during multiple dosing, the dose is equal to the product of _____________.
Vd and Clearance
Clearance and Steady state
Clearance and Plasma concentration
Loading dose and Clearance
Every 12 hours, once a day, and QID is an example of
Loading dose
Maintenance dose
Dose frequency
Drug formulation
The lesser the drug profile (size), the lesser the fluctuations, making the drug effective.
True
False
Maybe
When the first drug concentration remaining in a body after certain time is added to the next dose during multiple dosage regimen, it is called ____________.
Build-up principle
Accumulation
Plateau
Steady state
An increase in dose in multiple dosing leads to the following effects, EXCEPT:
Increase in C(mean)
Increase risk of side effects for drugs with NTI
Larger difference between C(max) and C(min)
Larger incovenience for patients
When the ratio of loading dose to maintenance dose is less than the half-life, the dose ratio is ____________.
Greater than 2.0
Less than 2.0
Equal to 2.0
NOTA
The extent to which a drug accumulates in the body during multiple dosing is independent of the ___________.
dose ratio
dose size
dose frequency
clearance
The manner in which a drug is taken is defined by the following, EXCEPT:
The volume of distribution of drug
The loading dose
The interval between doses
The drug formulation
Which of the following do you think is NOT an importance of observing proper dosage regimen?
It establishes safety and efficacy of drugs.
It reduces the risks of possible drug-drug interactions.
It is helpful in assessing the patients needs for treatment.
It determines the optimum quality response of drugs to special populations.
Select the odd one out.
Steady state
Infusion equilibrium
Peak concentration
Plateau
On continuous steady administration of a drug, what will happen to the plasma concentration?
It will rise gradually and eventually reach a plateau in a fast rate.
It will rise immediately until it reaches plateau.
It will slowly rise fast at first then more slowly and reach a plateau.
It will rise fast at first then more slowly and reach a plateau.
