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Pharma Chapter 26: Analgesics and Antihistamines

Total questions: 20

Worksheet time: 20mins

Name
Class
Date
1.
Which is not a class of anti-inflammatory drug?
a)
Opioids
b)
COX inhibitors
c)
Antirheumatoid drugs
d)
Anticytokines and other biological agents
2.
Cyclo-oxygenase inhibitors do NOT include
a)
Chloroquine
b)
Asprin
c)
Ibuprofen
d)
Celecoxib
e)
Acetominophen
3.
Which is NOT an effect of NSAIDs?
a)
Anti-coagulant
b)
Anti-inflammatory
c)
Analgesic
d)
Antipyretic
4.
Which drug has previously been stigmatized as cardiotoxic?
a)
Celecoxib
b)
Ibuprofen
c)
Acetominophen
5.
Which drug is shows pronounced liver toxicity in high doses?
a)
Celecoxib
b)
Ibuprofen
c)
Acetominophen
6.
In terms of therapeutic onset, DMARDS are
a)
Very fast (days)
b)
Fast (weeks)
c)
Slow (months)
d)
Very slow (years)
7.
Which is not a class of immunosuppressants?
a)
IL-2 inhibitors
b)
Cytokine inhibitors
c)
Purine/pyramidine synthesis inhibitors
d)
NSAIDs
8.
Which is NOT for acute treatment of gout?
a)
NSAIDS
b)
Glucocorticoids
c)
Colchicine
d)
Allopurinol
9.
Which isoform is more widely expressed, especially in places like the stomach lining?
a)
COX1
b)
COX2
10.
Which isoform is upregulated during inflammation?
a)
COX1
b)
COX2
11.
Which side effect would NOT be anticipated with NSAIDs?
a)
Low blood pressure
b)
A small rash
c)
Renal failure
d)
Abdominal pain
12.
Which is not a DMARD?
a)
Cyclosporin
b)
Methotrexate
c)
Sulfasalazine
d)
Penicillamine
e)
Chloroquine
13.
Which of these is an IL-2-specific immunosuppressant?
a)
Cyclosporin
b)
Cortisol
c)
Chloroquine
d)
Abatacept
e)
Adalinumab
14.
Which of these is not a biopharmaceutical?
a)
Sulfasalazine
b)
Infliximab
c)
Adalinumab
d)
Anakinra
e)
Abatacept
15.
Which of these is a purine synthesis inhibitor?
a)
Azathioprine
b)
Adalinumab
c)
Anakinra
d)
Abatacept
e)
Allopurinol
16.
Which of these is NOT used for acute treatment of gout?
a)
Allopurinol
b)
NSAIDs
c)
Glucocorticoids
d)
Colchicine
17.
Which of these prophylactic gout treatments reduces uric acid PRODUCTION (not excretion)
a)
Allopurinol
b)
Probenecid
18.
Which histamine receptor, when blocked, leads to an anti-inflamatory response?
a)
H1
b)
H2
c)
H3
19.
Which was the first non-sedating anti-histamine?
a)
Diphenhydramine
b)
Terfenadine
c)
Loratadine
20.
Which of the three NSAID qualifications does acetominophen not fill?
a)
Anti-inflammatory
b)
Analgesic
c)
Antipyretic