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Toxi Lect - Quiz 1

Total questions: 25

Worksheet time: 16mins

Name
Class
Date
1.

This antidote neutralizes severe human DIGOXIN poisoning.

a)

Dicobalt edetate

b)

BAL

c)

Digoxin FAB

d)

4-DMAP

2.

This antidote is specific for Benzodiazepine overdose by competitively inhibiting activity at the GABA-receptor complex.

a)

Ethanol

b)

Flumazenil

c)

Flurazepam

d)

Ocreotide

3.

Atropine is the antidote for the ff. drug poisoning, EXCEPT:

a)

Pyridostigmine

b)

Sarin, soman, tabun

c)

Propranolol

d)

Antihistamine

4.

Therapeutic dose for severe atropine poisoning.

a)

1-2 g/day

b)

1-2 mg/kg IV

c)

10mg IV

d)

0.015 - 0.05 mg/kg

5.

Dose of Calcium gluconate for dental or oral hydrofluoric acid exposure.

a)

2.5 gel into exposed areas for 15 minutes

b)

30mL of 10% calcium gluconate over 5 minutes

c)

0.2mL/kg up to 10 mL IV

d)

0.1-0.3 mL/kg of 10% Ca chloride

6.

This antidote affects calcium flux across the sarcoplasmic reticulum of skeletal muscle cells resulting in rapid resolution of hyperthermia, dysrrhythmias, and muscle rigidity.

a)

Amyl nitrite

b)

Deferoxamine

c)

Dicobalt edetate

d)

Dantrolene

7.

Expanded version of EDTA which enhances elimination of radionuclides and metals from the body by exchanging organic compounds for inorganic ions.

a)

Calcium disodium edetate

b)

Diethylenetriaminepentaacetic acid

c)

4-DMAP

d)

4-aminopyridine

8.

Specific for sulfonylurea-induced hyperinsulinemia

a)

Ocreotide

b)

Dantrolene

c)

Dextrose

d)

Dicobalt edetate

9.

Maintenance dose of ETHANOL in methanol posoining.

a)

100 mg/Dl

b)

1.4 mL/kg/hour of 10% ethanol in D5W

c)

7.6-10 mL/kg of 10% ethanol in D5W

d)

0.2 mg bolus IV

10.

Dose of Benztropine for dystonic reactions.

a)

1-2mg/kg up to 50mg IM

b)

1-2mg/kg IV

c)

1-2mg IM

d)

50-75mg/kg/day in 3 divided doses

11.

Used for cyanide poisoning. It acts by forming a nontoxic stable ion complex with cyanide.

a)

Digibind

b)

Calcium chloride

c)

Amyl nitrite

d)

Dicobalt edetate

12.

Specific antidote for Eaton-Lambert syndrome.

a)

Aminophylline

b)

Atropine

c)

4-Aminopyridine

d)

4-DMAP

13.

The DOC for cyanide poisoning in Germany. It is useful in cyanide poisoning following prolonged use of sodium nitroprusside.

a)

4-DMAP

b)

BAL

c)

Sodium nitrite

d)

Sodium thiosulfate

14.

This drug acts by antagonizing the depressant action of adenosine by competitively binding to adenosine receptors thus producing bronchodilation.

a)

Aminopyridine

b)

Antihistamine

c)

Aminophylline

d)

Acetylcholine

15.

Antidote best used for ocular exposures to calcium oxide, lime and cement.

a)

EDTA

b)

BAL

c)

Atropine

d)

Dicobalt edetate

16.

Antihistamines are helpful in relieving dystonias associated with the ff. antipsychotic drugs.


You can select more than 1 answer.

a)

Phenothiazine

b)

Metoclopramide

c)

Thioxanthenes

d)

Haloperidol

e)

AOTA

17.

Dantrolene is used for the ff. conditions:


You can select more than 1 answer.

a)

Neuroleptic malignant syndrome

b)

Organophosphate poisoning

c)

Carbon monoxide poisoning

d)

Bromate and chlorate poisoning

18.

Long term use of Deferoxamine mesylate causes the ff. adverse reactions:


You can select more than 1 answer.

a)

Night blindness

b)

Optic neuropathy

c)

Urticaria

d)

Erythema

e)

Hearing loss

19.

Uses of 4-aminopyridine


You can select more than 1 answer.

a)

Inocybe mushroom poisoning

b)

Betanechol poisoning

c)

Pancuronium overdose

d)

Eaton-Lambert syndrome

e)

Neostigmine and Pyridostigmine reversal

20.

The ff. are cautions in administering Ca chloride and Ca gluconate:


You can select more than 1 answer.

a)

Avoid in patient on glycosides

b)

Patients with leukopenia

c)

Should be given slowly via IV

d)

May cause fetal methemoglobinemia

e)

May cause hypercalcemia in patients with CKD

21.

Select the odd one out.


Cyanide antidotes

a)

Sodium nitrite

b)

Sodium thiosulfate

c)

Sodium nitrate

d)

Amyl nitrite

22.

Select the odd one out.


Uses of BAL in oil.

a)

Pain and sterile abscesses

b)

Gold poisoning

c)

Arsenic poisoning

d)

Inorganic mercury poisoning

23.

Select the odd one out.


Cautions in administering 4-DMAP.

a)

Patients with G6PD

b)

Brown discoloration of urine

c)

Hypertensive patients

d)

Hemolysis

24.

Select the odd one out.


Cautions in administering Digoxin Antibody

a)

Monitor serum K

b)

Monitor ECG

c)

Acute IgE-mediated hypersensitivity reaction

d)

Monitor serum Na

25.

Select the odd one out.


Dose of BAL

a)

3-5mg/kg IM every 4 hrs for 2 days

b)

3mg/kg IM every 6 hrs for 1 day

c)

3mg/kg IM every 12 hrs for 7 days

d)

3.25 mg/kg IM for 24 hrs.