WorksheetsJournal club
Total questions: 20
Worksheet time: 12mins
Intra-articular drug that most significantly improves pain and function in patients with knee osteoarthritis?
High density hyaluronic acid
Low density hyaluronic acid
Corticosteroids
platelet-rich plasma.
Is a common disease associated with progressive deterioration of the cartilage and narrowing of the joint space?
LCA tear
chronic knee trauma
Knee osteoarthritis
rheumatoid arthritis
Is a set of statistical tools, which are useful for synthesizing data from a collection of studies?
analytical study
meta-analysis
cohort study
retrospective study
This technique showed significantly more excellent or good results in chondral lesions at > 3-year follow-up…
microfracture (MF)
Autologous chondrocyte implantation (ACI)
Matrix-induced autologous chondrocyte implantation (MACI).
Osteochondral autograft transplantation (OAT)
It is an osteochondral transplant in which tissue is obtained from an area with less demand on the knee to cover a chondral defect in a more important area.
Mosaicplasty
Microfracture
Autologous chondrocyte implantation
Osteochondral autograft transplantation
The most frequent cause of chondral injuries?
Osteochondritis
Trauma
Chondropathy
Collagen type 1 failure
Hyaline cartilage and synovial fluids function, except:
prevents joint wear.
pain-free movement of synovial joints
joints damage repair
low-friction.
Often is consider first-line option in treating deep injuries articular cartilage due to its minimally invasive nature, its technical ease, limited surgical morbidity and its low cost
Autologous chondrocyte implantation
Osteochondral autograft transplantation
Mosaicoplasty
Microfracture
Is minimally invasive surgery hat promote bone bleeding to create a clot in the chondral defect whit holes 3 to 4 mm apart.
Osteochondral autograft transplantation
Microfracture
Autologous chondrocyte implantation
Mosaicoplasty
was initially described as a spontaneous condition that brings about detached pieces of the articular surface without any other considerable damage to the joint.
Collagen type 1 failure
Chondropathy
Osteochondritis dissecans
Chondral lesions
It is a technique by which the cartilage cells of the person himself are grown and multiplied in a specialized laboratory.
Matrix-induced autologous chondrocyte implantation (MACI).
microfracture (MF)
Autologous chondrocyte implantation (ACI)
Osteochondral autograft transplantation (OAT)
What is the main negative factor involved on microfracture in athletes?
The high cost in subsequent surgeries
A rapid repair response from progenitor cells
The possibility of doing sports again
Failures during surgery
The chondral lesions in knee joint mainly affect
the medial femoral condyle
the lateral femoral condyle
tibial plateau
Which is correct?
Microfracture is cost-effective initial treatment of defects .2 cm2
Microfracture is not a cost-effective initial treatment of defects .3 cm2
Microfracture is a cost-effective initial treatment of defects .3 cm2
Microfracture is not a cost-effective initial treatment of defects .2 cm2
Which is correct?
Osteochondral allografts transplantation of the patella or bipolar lesions is potentially cost-ineffective and should be used judiciously.
Osteochondral allografts transplantation of the patella or bipolar lesions is potentially cost-effective and should be used judiciously.
Osteochondral allografts transplantation of the patella or bipolar lesions is potentially cost-effective and should always be use on this patients
Osteochondral allografts transplantation isnt works
Which is correct?
Implantation of culture-expanded of Adiposederived mesenchymal stem cells is a safe and efficient procediment for full-thickness knee chondral lesions
Implantation of culture-expanded of Adiposederived mesenchymal stem cells is not a safe and efficient procediment for full-thickness knee chondral lesions
Implantation of culture-expanded of Adiposederived mesenchymal stem cells is a safe but inefficient procediment for full-thickness knee chondral lesions
Implantation of culture-expanded of Adiposederived mesenchymal stem cells is a safe and inefficient procediment for full-thickness knee chondral lesions
What is the approach to the use of mesenchymal stem cells?
To promote tissue regeneration, restoration of impaired function
Only to improve the clinic
For activate general cell regeneration
For improve only impaired function
which of the next factors gives ACI a better prognosis?
Symptoms <5 years
Concomintant procedures
Previous surgical treatment
Chondral lesion >8 mm deep
What does the Kaplan Meier analysis define?
Satistical significance if variables
The severety of symptoms in patients
Surival estunate if variables
Which of the next options is a source for mesenchyal stem cells to treat knee cartilage defects
Adipose tissue
gut mucus layer
Central nervous system
Peripheral nervous system
