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WorksheetsPrions
Total questions: 10
Worksheet time: 2mins
Prions are
circular RNA
enveloped DNA viruses
defective RNA viruses
Protozoans
misfolded brain proteins
Prions cause all of the following disease except
Creutzfeldt-Jakob disease
Scrapie
Kuru
Bovine Spongiform Encephalopathy
Lymphedema
Prions are infectious because they
cause other prions proteins to misfold
reproduce asexually
reproduce inside host cells
can be transferred in respiratory droplets
The incubation period for prion disease is
1-3 days
2-4 months
3-6 months
several months-several years
The main reservoir for prion disease is
brain and spinal cord tissue (animals and humans)
soil
water
bats
ticks
A virulence factor of prions is
resistance to destruction
glycoprotein spikes
a neurotoxin
fimbraie
Prions can be spread by
eating meat or other foods contaminated with brain and spinal cord tissue containing prions
sharing needles
contaminated surgical equipment
contact with blood
Signs and symptoms of prion disease include
Fatigue
Muscle stiffness
Hallucinations
Swollen lymph nodes
High fever
How can Prion disease be prevented?
Destroy infected feed animals
Remove brain, spinal cords, and placentas from meat products
A toxoid vaccine
Chloroquine
Broad spectrum antibiotics including tetracycline
Prion disease can be treated and is not always fatal.
True
False
