Font size
WorksheetsBasic Pharmacokinetics
Total questions: 10
Worksheet time: 8mins
The branch of pharmacology that deals with disposition and fate of drug is
Pharmacokinetic
Both
Pharmacodynamic
None
The application of pharmacokinetic principles in the safe and effective treatment of individual patients, and in the optimization of drug therapy
clinical pharmacy
clinical pharmacology
clinical biopharmaceutics
clinical pharmacokinetic
Which of the following statement is (are) correct?
pharmacodynamic parameters characterize the effects of a drug on the body
a receptor is that component of the body with which a drug interacts to produce its effects
pharmacokinetic parameters describe the effects of the body on a drug
the physicochemical properties of the drug is important in determining the fate of the drug
The partitioning of drug molecules among numerous locations in the body
excretion
metabolism
distribution
absorption
Drug absorption can be increase by
Increasing the blood flow to the site of administration
Increasing the surface area dedicated to absorption
Decreasing the pH when the drug is a weak base
Decreasing the drug particle size
Increasing the drug lipid solubility
What is the phenomena that cause reduction of drug concentration before it reaches the systemic circulation?
(a)
Bioequivalence documentation may be useful to
Link early and late phase clinical formulations
Evaluate changes of solid dose formulation
Compare clinical versus to-be-marketed formulation
Compare generic versus branded drug
The therapeutic index is the degree of separation between ___________ and _____________ doses.
(a)
What is the important enzyme in phase 1 of drug metabolism?
(a)
The common wastes excreted is (are)
saliva
perspirant
bile
gas
