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WorksheetsGene Regulation
Total questions: 20
Worksheet time: 10mins
All the genes in both a prokaryotic cell and a eukaryotic cell are expressed at the same time.
True
False
Prokaryotes regulate gene expression primarily
in order to maintain homeostasis
in response to changing environmental conditions
during development as cells specialize
Prokaryotes do not regulate gene expression. All genes are always on.
One way to regulate the expression of a gene is to control the formation of mRNA. This is called ___ control.
transcriptional
translational
post-transcriptional
post-translational
In order for a gene to be expressed, ___ must bind to the gene's ___, a specific sequence of nucleotides at one end of the gene, thus initiating transcription.
DNA polymerase, promotor
DNA polymerase, operator
RNA polymerase, promotor
RNA polymerase, operator
An operon is
a genetic on/off switch in prokaryotes
a genetic on/off switch in eukaryotes
a group of related genes and the associated gene switches in prokaryotes
a group of related genes and the associated gene switches in eukaryotes
Genes can be shut off (not expressed) when a ___ binds to the ____.
activator, operator
repressor, operator
corepressor, operator
repressor, promotor
What molecule can remove a repressor protein from the operator?
a corepressor
an inducer
What is the inducer in the lac operon?
cAMP
glucose
lactose
CRP
Genes can be turned on (expressed) when a(n) ____ such as CRP or cAMP receptor protein binds to the CRP binding site.
repressor
corepressor
inducer
activator
In the lac operon system, __ must first bind to CRP so that it is capable of binding to the DNA. This occurs when glucose levels are __.
cAMP, high
cAMP, low
inducer, high
inducer, low
Negative control of gene expression is mediated by __ and results in a(n) __ in the frequency of transcription.
activators, increase
activators, decrease
repressors, increase
repressors, decrease
In the trp operon, __ acts as a __ and helps the repressor bind to the operator.
tryptophan, corepressor
tryptophan, inducer
lactose, corepressor
lactose, inducer
The trp operon has only ___ control which is common for the genes needed for ___ processes.
positive, catabolic
positive, anabolic
negative, catabolic
negative, anabolic
Eukaryotes need to regulate their genes
during cell specialization that occurs during development
in order to maintain homeostasis
both a and b
neither a or b
Which of the following is/are similarities between prokaryotic and eukaryotic gene expression?
both use proteins to interact with the DNA to control gene expression
both have histones complexed with their DNA
both separate the processes of transcription and translation spatially
all of the above
___ are DNA sequences which are often located far from the genes they regulate in eukaryotes where transcription activators can bind.
histones
promotors
enhancers
Which of the following help to turn genes on so that they are expressed (transcribed and translated)?
a high level of condensation (coiling around histones)
histone acetylation
DNA methylation
histone methylation
Inheritance NOT involving the nucleotide sequence of the DNA but involving chromatin modifications such as methylation is called
epigenetic inheritance
antigenetic inheritance
Which of the following are types of post-transcriptional control of genes in eukaryotes?
alternative RNA splicing or processing
gene silencing through RNA interference
destruction of ubiquitin tagged proteins
all of the above
Alternative RNA splicing involves
removing introns and splicing the same exons together
removing exons and splicing the same introns together
removing introns and splicing different exons together
removing exons and splicing different introns together
